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FTI-2153 Catalog No.:M27128-C Edronax mesylate

SKU: 55349776140

4.6
USD100.00 USD129.00

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Description

Edronax mesylate

in vivo: Treatment with docetaxel alone at the maximal tolerated dose (MTD) showed an apparent antitumor activity to an intrinsically resistant HCT-15 tumor xenograft

Smiles: [2H]C1([2H])N(CC(=O)C2=CC(C3NC(=O)C4=C(N=3)C(CCC)=NN4C)=C(C=C2)OCC)C([2H])([2H])C([2H])([2H])N(CC)C1([2H])[2H]

6-trifluorophenyl)methyl]-12-oxa-2

FTI-2153 Catalog No.:M27128-C Edronax mesylateFTI 2153 is a potent and highly selective inhibitor of farnesyltransferase (FTase), with an IC50 of 1. 4 nM. FTI 2153 is >3000 fold more potent at blocking H Ras (IC50, 10 nM) than Rap1A processing. Anti cancer activity. Product information CAS Number: 344900 92 1 Molecular Weight: 466. 60 Formula: C25H30N4O3S Chemical Name: methyl (2S) 2 {[5 ({[(1H imidazol 5 yl)methyl]amino}methyl) 2' methyl [1,1' biphenyl] 2 yl]formamido} 4

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